Allison E. DeVan, Ph.D.

Postdoctoral Research Fellow/Research Faculty

Integrative Physiology of Aging Laboratory

University of Colorado at Boulder

Office: (303) 492-4975 • Fax: (303) 492-6778 • allison.devan@colorado.edu

 

Research Focus: the effects of aging, exercise, nutraceuticals and disease on

endothelial function and large elastic artery stiffness in humans

 

Postdoctoral Training, Integrative Physiology, University of Colorado, 2010-present

                                             Mentor: Douglas Seals

    Doctor of Philosophy, Exercise Physiology, The University of Texas at Austin, 2009

                                             Mentor: Hirofumi Tanaka

           Master of Arts, Exercise Physiology, The University of Texas at Austin, 2004

                                             Mentor: Hirofumi Tanaka

           Bachelor of Science, Exercise Science, The University of Georgia, 2002

                                             Mentor: Kevin McCully

 

Publications

Sindler AL; DeVan AE; Fleenor BS; Seals DR.  Inorganic nitrite supplementation for healthy arterial aging.  J Appl Physiol, in press, 2014.

 

DeVan AE; Eskurza I; Pierce GL; Walker AE; Jablonski KL; Kaplon RE; Seals DR.  Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging.  Clinical Science (London), 124: 325-331, 2013.  PMC3509933 [Article]

 

DeVan AE; Pierce GL; Brooks FA; Seals DR.  The dependence of FMD% on baseline diameter: a problem solved by allometric scaling.  Reply: No problem in this case.  Clinical Science (London), 125: 55-56, 2013.

 

DeVan AE and Seals DR.  Vascular health in the ageing athlete, Experimental Physiology, 97.3: 305-310, 2012. PMC3303941 [Article]

 

Pierce GL; Jablonski KL; Walker AE; Seibert SM; DeVan AE; Black SM; Sharma S; Seals DR.  Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: A pilot study.  Am J Hypertension, 25: 1050-1054, 2012. PMC3482981 [Article]

 

Parkhurst K; Lin H; DeVan AE; Barnes JN; Tarumi T; Tanaka H.  Contribution of blood viscosity to flow-mediated dilation and measures of arterial stiffness, Vascular Medicine, 17:231-234, 2012.

 

DeVan AE; Umpierre D; Lin H-F;  Harrison ML; Tarumi T; Dhindsa M; Hunter SD; Sommerlad SM; Tanaka H.  Habitual resistance exercise and endothelial ischemia-reperfusion injury in young adults, Atherosclerosis, 219: 191-193, 2011.

 

Dhindsa M; Barnes JN; DeVan AE; Sugawara J; Tanaka H.  Comparison of augmentation index derived from multiple devices.  Artery Research, 5: 112-114, 2011.

 

DeVan AE; Umpierre D; Harrison ML; Lin H; Tarumi T; Renzi CR; Dhindsa M; Hunter SD; Tanaka H. Endothelial ischemia-reperfusion injury in humans: association with age and habitual exercise. Am J Physiol Heart Circ Physiol, 300: H813-92, 2011. PMC3064302 [Article]

 

Ley O; Dhindsa M; Sommerlad SM; Barnes JN; DeVan AE; Naghavi M; Tanaka H. Use of temperature alterations to characterize vascular reactivity.  Clin Physiol Funct Imaging, 31: 66-72, 2011.

 

Tanaka H; DeVan AE; Barnes JN. Commentaries on viewpoint: pick your Poiseuille: normalizing the shear stimulus in studies of flow-mediated dilatation. J Appl Physiol, 107: 1361-1362, 2009.

 

Dhindsa MS; Sommerlad SM; DeVan AE; Barnes JN; Sugawara J; Ley O; Tanaka H.  Inter-relationships among noninvasive measures of postischemic macro- and micro-vascular reactivity.  J Appl Physiol, 105: 427-432, 2008. PMC2519948  [Article]

 

Cortez-Cooper MY; Anton MM; DeVan AE; Neidre D; Cook JN; Tanaka H.  The effects of strength training on central arterial compliance in middle-aged and older adults.  Eur J Cardiovasc Prev Rehab, 15: 149-155, 2008.

 

Dhindsa MS; Barnes JN; DeVan AE; Nualnim N; Tanaka H.  Innovative exercise device that simulates horseback riding: cardiovascular and metabolic responses.  Comp Exercise Physiol, 5: 1-5, 2008.

 

DeVan AE; Tanaka H.  Declines in ten-pin bowling performance with advancing age.  Age and Ageing, 36: 693-694, 2007.  [Article]

 

Anton MM; Cortez-Cooper M; DeVan AE; Neidre D; Cook JN; Tanaka H.  Resistance training increases basal limb blood flow and vascular conductance in aging humans.  J Appl Physiol, 101: 1351-1355, 2006.  [Article]

 

Cook JN; DeVan AE; Schleifer JL; Anton MM; Cortez-Cooper MY; Tanaka H.  Arterial compliance of rowers: implications for combined aerobic and strength training on arterial elasticity.  Am J Physiol Heart Circ Physiol, 290:1596-600, 2006.  [Article]

 

Anton MM; Cortez-Cooper MY; DeVan AE; Neidre DB; Cook JN; Tanaka H.  Cigarette smoking, regular exercise, and peripheral blood flow.  Atherosclerosis, 185: 201-5, 2006.

 

DeVan AE; Anton MM; Cook JN; Neidre DB; Cortez-Cooper MY; Tanaka H.  Acute effects of resistance exercise on arterial compliance.  J Appl Physiol, 98: 2287-91, 2005.  [Article]

 

Cortez-Cooper MY; DeVan AE; Anton MM; Farrar RP; Beckwith KA; Todd JS; Tanaka H.  Effects of high intensity resistance training on arterial stiffness and wave reflection in women.  Am J Hypertens, 18: 930-4, 2005.

 

DeVan AE; Lacy BK; Cortez-Cooper MY; Tanaka H.  Post-exercise palpation of pulse rates: its applicability to habitual exercisers.  Scand J Med Sci Sports, 15: 177-81, 2005.

 

Sugawara J; Hayashi K; Yokoi T; Cortez-Cooper MY; DeVan AE; Anton MA; Tanaka H.  Brachial-ankle pulse wave velocity: an index of central arterial stiffness?  J Hum Hypertens, 19: 401-6, 2005.

 

Olive JL; DeVan AE; McCully KK.  The effects of aging and activity on muscle blood flow.  Dynamic Medicine, 1:2, 2002. PMC150384 [Article]

 

Funding

University of Colorado Denver Aging Training Grant, National Institute on Aging, AG27910, “Efficacy of Cholecalciferol Supplementation for Improving Large Elastic Artery Stiffness in Middle-Aged and Older Adults with Serum 25-Hydroxyvitamin D Deficiency”, 2011-2013

 

National Research Service Award, National Institute on Drug Abuse, Ruth L. Kirschstein Predoctoral Individual Fellowship, DA018431, “Smoking and exercise on arterial stiffness”, 2005-2008

 

Abstracts

DeVan AE; Brooks FA; Evans TD; Bassett CJ; Santos-Parker JR; Sindler AL; Chonchol MB; Bryan NS; Giordano T; Seals DR.  Safety and efficacy of sodium nitrite supplementation for improving vascular endothelial function in middle-aged and older healthy adults.  FASEB J, in press, 2014.

 

DeVan AE; Eskurza I; Pierce GL; Walker AE; Jablonski KL; Kaplon RE; Seals DR.  Impaired fasting blood glucose-related exacerbation of age-associated vascular endothelial dysfunction: Protective effect of regular aerobic exercise.  FASEB J, 26:865.2, 2012.            

 

Racine ML; Geolfos CJ; DeVan AE; Gates PE; Chonchol MB; Seals DR; Jablonski KL.  Enhanced tetrahydrobiopterin contributes to sodium restriction–induced improvements in large elastic artery compliance in older adults with elevated systolic blood pressure.  FASEB J, 26:1131.11, 2012.

 

DeVan AE; Umpierre D; Lin HF; Harrison ML; Tarumi T; Renzi CP; Dhindsa M; Hunter SD; Tanaka H.  Endothelial ischemia-reperfusion injury in humans: Association with age and habitual exercise.  FASEB J, 25: 818.7, 2011.

 

DeVan AE; Pierce GL; Walker AE; Jablonski KL; Seals DR.  Vascular endothelial function and systemic markers of oxidative modification, antioxidants and inflammation in adults without clinical disease.  FASEB J, 25: 818.8, 2011.

 

Dhindsa MS; Sommerlad SM; DeVan AE; Barnes JN; Sugawara J; Tanaka H. Inter-relationships between noninvasive measures of peripheral vascular reactivity.  FASEB J, 22: 967.6, 2008.

 

Dhindsa MS; Barnes JN; DeVan AE; Nualnim N; Tanaka H.  Innovative exercise device that simulates horseback riding: Cardiovascular responses. Med Sci Sports Exerc, 39: S352, 2007.

 

Anton MM; Cortez-Cooper MY; DeVan AE; Neidre DB; Cook JN; Tanaka H.  Resistance training increases basal limb blood flow and vascular conductance in aging humans.  FASEB J, 20: A813-A814, 2006.

 

Cortez-Cooper MY; Anton MM; DeVan AE; Neidre DB; Cook JN.  Effects of strength training vs. stretching on central arterial compliance in older adults.  FASEB J, 20: A814, 2006.

 

Cook JN; DeVan AE; Schleifer JL; Anton MM; Cortez-Cooper MY; Tanaka H. Arterial compliance of rowers: Implications for combined aerobic and strength training on arterial elasticity.  Med Sci Sports Exerc, 38: S184, 2006. 

 

DeVan AE; Anton MM; Cook JN; Cortez-Cooper MY; Neidre DB; Tanaka H.  Acute effects of resistance exercise on central arterial compliance.  Med Sci Sports Exerc, 37: S136, 2005.

 

DeVan AE; Lacy BK; Cortez-Cooper MY; Tanaka H.  Post-exercise palpation of pulse rates: Its applicability to trained individuals.  Med Sci Sports Exerc, 36: S4, 2004.

 

Cortez-Cooper MY; DeVan AE; Anton MM; Farrar RP; Beckwith KA; Todd JS; Tanaka H.  The effects of strength training on arterial stiffness in women. Med Sci Sports Exerc, 36: S50, 2004. 

 

Presentations, Teaching, and Lectures

Invited Presentation, “Vascular Health in the Ageing Athlete”, Biomedical Basis of Elite Performance, London, England, Mar 2012

 

Co-Instructor, Professional Skills for the Research Scientist, Graduate Course, Fall 2011

 

Co-Instructor, Integrative Physiology of Aging, Graduate Course, Fall 2010

 

Guest Lecturer, Physiological Basis of Conditioning, Undergraduate Course, Feb 2009

 

Guest Lecturer, Exercise Physiology, Undergraduate Course, Feb 2009

 

Teaching Assistant, Physiological Basis of Conditioning, Undergraduate Course, Spring 2008 & 2009

 

Guest Lecturer, Clinical Exercise Physiology: Theory & Practice, Graduate Course, Nov 2007

 

Laboratory Teaching Assistant, Clinical Exercise Physiology Laboratory, Graduate Lab, Fall 2007

 

Guest Lecturer, Physiology of Exercise, Undergraduate Course, Apr 2007

 

Laboratory Teaching Assistant, Physiology of Exercise, Undergraduate Lab, Spring 2007

 

“Acute Effects of Resistance Exercise on Arterial Stiffness”, American College of Sports Medicine National Annual Meeting, Nashville, Tennessee, Jun 2005

 

Guest Laboratory Lecturer, Clinical Exercise Physiology Laboratory, Graduate Lab, Sept 2004

 

“Post-Exercise Palpation of Pulse Rates: Its Applicability to Trained Individuals”, American College of Sports Medicine National Annual Meeting, Indianapolis, Indiana, May 2004

 

Teaching Assistant, Weight Training, Undergraduate Course, 2002-2003

 

Teaching Assistant, Cardiovascular and Weight Training, Undergraduate Course, 2003

 

Professional Service

Safety Monitoring Committee Investigator Representative, Clinical Translational Research Center, University of Colorado at Boulder, 2010 - present

 

Mentor, McNair Intellectual Entrepreneurship Program, The University of Texas at Austin and St. Edwards University, assisting McNair undergraduate scholars in graduate school preparations, Jan 2008 – Dec 2008

 

Reviewer of manuscripts for: Hypertension (2013), Journal of Applied Physiology (2008, 2010, 2011, 2012, 2013), American Journal of Physiology-Heart and Circulatory Physiology (2010, 2012), Dynamic Medicine (2006)

 

Member, American Heart Association, 2003 – present

 

Member, American Physiological Society, 2002 – present

 

Member, American College of Sports Medicine, 2002 – present

 

Specialties

Grant Writing (including NRSA, T32, R21 and R01 applications), NIH Grant Management, Study Design, Human Subjects Recruitment, Study Management, Data Analysis, Manuscript Preparation, Food and Drug Administration Investigational New Drug Applications and Annual Reports, Institutional Review Board Applications, Literature Review, Vascular Endothelial Function, Large Elastic Artery Stiffness, Blood Pressure, Pulse Wave Velocity, Carotid Compliance, Carotid Beta-Stiffness Index, Flow-Mediated Dilation, Venous Occlusion Plethysmography, Arterial Tonometry, Oxidative Stress, Inflammation, Circulating Analytes, Resistance Exercise, Aerobic Exercise, Lifestyle Interventions, Vascular Ischemia-Reperfusion Injury, Vitamin D, Sodium Nitrite