Figure 10



Classes of G protein-coupled receptors (GPCR) and the G proteins they regulate. Currently, the Falke group is studying the formylated peptide receptor (FPR) which couples to the G-alpha-i type of heterotrimeric G protein. This receptor initiates the eukaryotic chemotaxis pathway that enables neutrophils and macrophage to migrate toward invading bacterial that release N-formylated peptides. For reviews on GPCRs see the GPCRDB website.





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