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Candace J. Geolfos, B.A. Professional Research Assistant Integrative Physiology of Aging Laboratory Department of Integrative Physiology University of Colorado at Boulder, 354 UCB Boulder, CO 80309-0354, USA Email: Candace.Geolfos@colorado.edu
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Current Research Projects Efficacy of oral nitrite therapy for treating arterial stiffness and endothelial function in healthy middle-aged and older adults. Efficacy of cholecalciferol (vitamin D3) supplementation for improving vascular endothelial function in middle-aged and older adults with serum 25-hydroxyvitamin D deficiency and insufficiency. |
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Research Experience
Integrative Physiology of Aging Laboratory, Undergraduate Assistant
Responsibilities: Subject recruitment Subject screening and testing Scheduling Data management Wet lab procedures Hazardous Waste Proctor
Techniques/ Skills: Graded Exercise Tests VO2 Max Testing Flow Mediated Dilation Venous Occlusion Plethysmography In Vitro Isolated Vessel Vascular Reactivity
Wetlab Experience (Molecular and Cellular): Endothelial Cell Collection and Processing DNA Extraction Mononuclear Cell Isolation Electron Paramagnetic Resonance Ex-Vivo Whole Blood Cytokine Production
Software: Microsoft Excel Microsoft Word Microsoft Powerpoint Microsoft Publisher
Publications Manuscripts:
Jablonski KL, Racine ML, Geolfos CJ, Gates PE, Chonchol M, McQueen MB & Seals DR. (2012). Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged and older adults with moderately elevated systolic blood pressure. J Amer Coll Cardiol 61:335-343, 2013; PMID: 23141486; NIHMSID: 431544. Jablonski KL, Fedorova OV, Racine ML, Geolfos CJ, Fleenor BS,Chonchol M, Bagrov AY, Lakatta EG and Seals DR. Reductions in aortic stiffness and systolic blood pressure with dietary sodium restriction are related to lowered renal marinobufagenin excretion (in review, Clin J Am Soc Nephrol)
Abstracts:
Jablonski KL, Seals DR, Racine ML, Geolfos CJ, Fleenor BS and Chonchol M. Higher potassium intake is associated with reduced large elastic artery stiffness, oxidative stress and inflammation in healthy middle-aged and older adults. J Am Soc Nephrol. 22: FR-PO1022, 2012
Jablonski KL, Fedorova OV, Chonchol M, Racine ML, Geolfos CJ, Fleenor BS, Bagrov AY, Lakatta EG and Seals DR. Marinobufagenin and dietary sodium restriction: Influences on blood pressure and large elastic artery stiffness. J Am Soc Nephrol. 22:FR-PO407, 2012
Racine ML, Geolfos CJ, DeVan AE, Gates PE, Chonchol M, Seals DR & Jablonski KL. (2012). Mechanisms of improved carotid artery compliance with dietary sodium restriction in middle-aged and older adults with moderately elevated systolic blood pressure. FASEB J.26: 1131.11, 2012
Marshall KD, Seals DR, Geolfos C, Lesniewski LA, Fleenor BS. (2010). Habitual aerobic exercise reverses age-associated increases in transforming growth factor beta 1 in carotid arteries of mice. FASEB Journal, 24:790.6.
Other Interests: Slalom Water-skiing Snowboarding Boating Camping Hunting Fishing Soccer Hiking Softball Piano |
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Education B.A. in Integrative Physiology with a Neuroscience Certificate and emphasis in Pre-Medicine University of Colorado at Boulder, May 2010 |
