Topic 6: Chaperones and Genetic Noise - Toby Franks Sternberg N. 1973. Properties of a mutant of Escherichia coli defective in bacteriophage lambda head formation (groE). I. Initial characterization. J Mol Biol. 1973 May 5;76(1):1-23. Sternberg N. 1973. J Mol Biol. 1973 May 5;76(1):25-44. Queitsch C, Sangster TA, Lindquist S. Nature. 2002 Jun 6;417(6889):598-9. Hsp90 as a capacitor of phenotypic variation. Sollars V, Lu X, Xiao L, Wang X, Garfinkel MD, Ruden DM. Nat Genet.
2003 Jan;33(1):70-4.Evidence
for an epigenetic mechanism by which Hsp90 acts as a capacitor for
morphological evolution. |
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Topic 6: Neural Noise - Chris Wrobel (part 1) & Xin Geng(part 2) HODGKIN AL, HUXLEY AF, KATZ B. J Physiol. 1952 Apr;116(4):424-48. Measurement of current-voltage relations in the membrane of the giant axon of Loligo. HODGKIN AL, HUXLEY AF. J Physiol. 1952 Apr;116(4):449-72.Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. HODGKIN AL, HUXLEY AF. HODGKIN AL, HUXLEY AF. Katz B, Miledi R. Katz B, Miledi R. Neher E, Sakmann B. Nature. 1976 Apr 29;260(5554):799-802. Single-channel currents recorded from membrane of denervated frog muscle fibres |
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Topic 5: Gene expression - Ka Lin Swain (part 1) & Nathan Gomes (part 2) Berg, H.C. & D.A Brown. 1972. Chemotaxis in E. coli analyzed by three-dimensional tracking. Nature 239:500-504. (background). Spudich, J.L. & D.E. Koshland, Jr. 1976. Non-genetic individuality: chance in the single cell. Nature 262: 467-471. MacAdams, H. & A. Arkin. 1997. Stochastic mechanisms in gene expression. Proc. Natl. Acad. Sci. USA 94:814-9. Ozbudak, E.M., M. Thattai, I. Kurster, A.D. Grossman & A.van Oudenaarden. 2002. Regulation of noise in the expression of a single gene. Nature Genetic 31:69-73. Blake, W.J., M. Kaern, C.R. Canter & J.J. Collins. 2003. Noise in eukaryotic gene expression. Nature 422:633-637. Fraser, H.B., A.E. Hirsh, G. Giaever, J. Kumm & M.B. Eisen. 2004. Noise minimization in eukaryotic gene expression. PLoS Biol. 2:e167. |
Topic 4: DNA Structure - Megan Wemmer Chargaff, E. 1950. Chemical specificity of nucleic acids and mechanism of their enzymic degradation. Experientia 6:201-209. Background on Chargaff Franklin, R. Gosling. 1953. Molecular configuration in sodium thymonucleate. Nature 171:740-741. Watson, J. & F. Crick. 1953. A structure for deoxyribose nucleic acid. Nature 171: 737-738. Allemand JF, Bensimon D, Lavery R, Croquette V. 1998. Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A. 199895:14152- |
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Topic
3: Genetic Material -
Ryan Takeshita
Griffith, F. 1928. "The significance of Pneumococcal types." J. Hygiene 27:141-144. Avery, O.T., C.M. MacLeod & M. McCarty. 1944. Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types; Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated From Pneumococcus Type III. J. Exp. Med. 79:137-158. Hershey & Chase. Independent functions of viral protein and nucleic acid in growth of bacteriophage. J. Gen. Physiol. 36:39-56. Background on the discovery of DNA (as genetic material) |
| Topic
2: Plasma membrane -
Andrew Troy
Gorter, E. & F. Grendel. 1925. On bimolecular layers of lipids on the chromocytes off the blood. J. Exp. Med. 41: 439-443. Frye, L.D. & M. Edidin. 1970. The rapid intermixing of cell surface antigens after formation of mouse-human heterokaryons. J. Cell Science 7: 319-325. Singer, S.J. 2004. Some early history of membrane molecular biology. Annu. Rev. Physiol. 66:1-27 Van Meer, G., E.H. Stelzer, R.W. Wignaendts-van Resandt & K. Simons. 1987. Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells. J. Cell Bio. 105: 1623-1635. |
| Topic
1: Cytoskeleton - Justin Kuczynski
Gorter, E. & F. Grendel. 1925. On bimolecular layers of lipids on the chromocytes off the blood. J. Exp. Med. 41: 439-443. Frye, L.D. & M. Edidin. 1970. The rapid intermixing of cell surface antigens after formation of mouse-human heterokaryons. J. Cell Science 7: 319-325. Singer, S.J. 2004. Some early history of membrane molecular biology. Annu. Rev. Physiol. 66:1-27 Van Meer, G., E.H. Stelzer, R.W. Wignaendts-van Resandt & K. Simons. 1987. Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells. J. Cell Bio. 105: 1623-1635. |
| Updated: 9 September '05 | ![]() |