Kelly M. Schultz, Ph.D.
Postdoctoral Research Associate
Howard Hughes Medical Institute
Department of Chemical and Biological Engineering
University of Colorado at Boulder
3415 Colorado Ave.
Email: schultkm@colorado.edu
Phone: (860) 833-6659
Rapid rheological screening to identify conditions of biomaterial hydrogelation
This work systematically characterizes biocompatible hydrogel scaffolds as a function of total polymer concentration using multiple particle tracking microrheology, creating gelation state diagrams.
Gelation of covalently cross-linked PEG-heparin hydrogel
The goal of this work is to characterize the gelation kinetics and final state of a biocompatible hydrogelator as a function of cross-linker size, backbone functionality and total polymer concentration.
High-throughput rheology in a microfluidic device
This work combines microrheological characterization with sample preparation in a microfluidics device to maximize the number of samples while minimizing the amount of material required and sample preparation time.
Electrospinning cross-linking PEG-heparin hydrogels
The goal of this work is to correlate the ability to create a unique matrix structures by electrospinning of a covalently cross-linked hydrogels with the corresponding gelation transition and kinetics measured using multiple particle tracking microrheology.
Measuring the modulus and reverse percolation transition of a degrading hydrogel
Macro- and microrheology measurements create a complete history of hydrogel modulus through the reverse percolation transition during hydrolytic degradation.
Monitoring degradation of MMP-cleavable PEG hydrogels via multiple particle tracking microrheology
This work measures enzymatic hydrogel degradation as a model system to inform the complicated phenomena of cell-mediated degradation. The aim of this study is to quantify the heterogeneity of the material and rheological properties around the critical gel-sol transition.
The effect of dynamic cell-mediated degradation on a synthetic hydrogel scaffold in the pericellular regime during migration
The goal of this work is to measure the degradation and remodeling of a synthetic hydrogel scaffold during 3D cell encapsulation.